About us

A Szentágothai János Kutatóközpont a PTE korszerű, nemzetközi tudományszervezési és menedzsment normák szerint kialakított új intézménye, amely az élettudományi, élettelen természettudományi, valamint környezettudományi oktatás...

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Translational neuroscience research group

  • Research concept
  • Members
  • R and D results
  • Services
  • Laboratories, instruments
  • Galleries

Cellularis neurophysiology:

Recording in vivo neuronal activity with microelectrodes int he rodent brain, iontophoretic application of neurochemicals, voltammetric detection of monoamine neurotransmitters.

Small animal behavioral physiology and psychopharmacology:

Psychopharmacology of the brain reward systems in rodents. Implementation of the delayed reward choice paradigm in computer controlled formal (operant) behavioral apparatus.

Human psychophysiology:

Psychophysiological and cognitive behavioral assessment of higher order brain functions such as perception, anticipation, reward devaluation, decision making. Recording behavioral and neurophysiological (EEG) correlates of somatosensory, auditory and visual stimulus identification and selection .

http://www.neurobio.pte.hu/kutatas/index.html

  • Development of tools and equipment for microelectrophysiology (from 1995).
  • Microelectrode development and testing (from 2000)
  • Software development for electrophysiology (from 2006)
  • Behavioral testing apparatus for measurement of thermal pain threshold (2007-2009)

Applied systems neuroscience, drug development and validation

  • Development of novel testing techniques and methodology.
  • Development of novel equipment for testing.
  • Neurophysiological testing of bioactive environmental (chemical and electromagnetc) agents.
  • Research and development and formal education within the scope of the laboratory.
  • In vivo cellular laboratory: extracellular unit recording, stereotaxic apparaus, biollogical signal conditioning (amplifiers,filters, ADCs, measurement of voltage and current), constant current ganerators (for microiontophoresis).
  • Small animal behavior laboratory: general activity, open field test, elevated plus maze test, forced swim test, food-choice tests, computer controlled operant behavioral chambers, neurotoxic brain lesions, reversible brain inactivation, central/systemic administration of bioactive agents.
  • Human psychophysiology laboratory: high performance 32 channel biological amplifier (EEG, EMG, ECG, EOG), computer controlled behavioral apparatus. Current research 1) basic: neurophysiology of face perception; 2) applied: neurocognitve effects of non-ionising environmental electromagnetic fields.