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A Szentágothai János Kutatóközpont a PTE korszerű, nemzetközi tudományszervezési és menedzsment normák szerint kialakított új intézménye, amely az élettudományi, élettelen természettudományi, valamint környezettudományi oktatás...



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NanoSight NS300

Type of shared service: 
Core Facility: 

The Malvern Panalytical NanoSight NS300 Instrument provides an easy-to-use, reproducible platform for nanoparticle characterization, especially size characterization of extracellular vesicles. Particles in liquid suspension are loaded into a sample chamber. In the path of the beam the particles scatter the laser light which is easily collected by the microscope objective and is viewed with a digital camera. The camera captures a video of the particles moving under Brownian motion. The NS300 allows rapid analysis of the size distribution and concentration of all types of nanoparticles from 10 nm - 2 µm in diameter, depending on the instrument configuration and sample type. With the ability to be supplied with interchangeable laser modules and the introduction of a motorized filter wheel means different fluorescent labels can be analyzed.

Detectable particle size: 10nm - 2000nm

Lasers: 488nm (Blue), 532nm (Green)

Concentration: 109 particle / ml

NS300 can be applied in the development of different delivery system studies:

  • Viral vaccine research
  • Nano-toxicology and viral vaccine detection
  • Protein aggregation studies
  • Extracellular vesicle characterization in different stages of diseases
  • Exosome and microvesicle characterization