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A Szentágothai János Kutatóközpont a PTE korszerű, nemzetközi tudományszervezési és menedzsment normák szerint kialakított új intézménye, amely az élettudományi, élettelen természettudományi, valamint környezettudományi oktatás...

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  • Publikációk

The histology core facility offers competences and equipments in histology and performs routine work like sectioning of tissues or classical stains for researchers. It also assists in the setting up and optimizing of histological approaches specific for each scientific project.

Furthermore, our MicroBrightfield-Nikon systems - which includes the Neurolucida and Stereo Investigator softwares - enables the complex morphometrical quantification of microscopic structures.

Szolgáltatások

The Eclipse Ti-U uses Nikon’s world-famous CFI60 optical system and a wide choice of objectives for bright field, dark field, fluorescence, phase contrast, DIC and modulation contrast microscopy techniques.

The most advanced system for neuron tracing and reconstruction, quantitative neuron analysis, and 3D brain mapping.

Neurolucida is a microscopy system specifically designed for performing accurate neuron reconstructions directly from histological specimens. It is capable of over 500 quantitative morphometric analyses, including:

The number of dendrites, axons, nodes, synapses, and spines

The length, width, and volume of dendrites and axons

The area and volume of somas

The complexity and extension of neurons  

A Stereo Investigator system provides you with accurate, unbiased estimates of the number, length, area, and volume of cells or biological structures in a tissue specimen. It is a key research tool that has led to advances in numerous areas of neuroscience including neurodegenerative diseases, neuropathy, memory, and behavior, as well as other research fields including pulmonary research, spinal cord research, and toxicology.

Műszerek

Leica VT1200 S Fully automated vibrating blade microtome

The fully automated Leica VT1200 S vibrating blade microtome is designed to meet the highest sectioning demands for cutting fresh and fixed tissue in Neuroscience.

Leica CM1860 - Cryostat for Standard Applications in the Clinical Histopathology Laboratory

The Leica CM1860 is your perfect assistant for high-quality, fast and safe sectioning. This high-throughput cryostat delivers diagnostic confidence by reliably producing quality sections to help provide an accurate diagnosis - even with the most complicated tissue types.

Garai Krisztina
asszisztens
gakr@gamma.ttk.pte.hu
29168

2018

Long-Term Stress and Concomitant Marijuana Smoke Exposure Affect Physiology, Behavior and Adult Hippocampal Neurogenesis.

Long-Term Stress and Concomitant Marijuana Smoke Exposure Affect Physiology, Behavior and Adult Hippocampal Neurogenesis.

Rusznák K, Csekő K, Varga Z, Csabai D, Bóna Á, Mayer M, Kozma Z, Helyes Z, Czéh B.

Front Pharmacol. 2018 Jul 23;9:786. doi: 10.3389/fphar.2018.00786. eCollection 2018.

Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats.

Long-Term Stress Disrupts the Structural and Functional Integrity of GABAergic Neuronal Networks in the Medial Prefrontal Cortex of Rats.

Czéh B, Vardya I, Varga Z, Febbraro F, Csabai D, Martis LS, Højgaard K, Henningsen K, Bouzinova EV, Miseta A, Jensen K, Wiborg O.

Front Cell Neurosci. 2018 Jun 20;12:148. doi: 10.3389/fncel.2018.00148. eCollection 2018.

2017

Electron Microscopic Analysis of Hippocampal Axo-Somatic Synapses in a Chronic Stress Model for Depression.

Electron Microscopic Analysis of Hippocampal Axo-Somatic Synapses in a Chronic Stress Model for Depression.

Csabai D, Seress L, Varga Z, Ábrahám H, Miseta A, Wiborg O, Czéh B.

Hippocampus. 2017 Jan;27(1):17-27. doi: 10.1002/hipo.22650. Epub 2016 Sep 15.

Chronic stress affects the number of GABAergic neurons in the orbitofrontal cortex of rats.

Chronic stress affects the number of GABAergic neurons in the orbitofrontal cortex of rats.

Varga Z, Csabai D, Miseta A, Wiborg O, Czéh B.

Behav Brain Res. 2017 Jan 1;316:104-114. doi: 10.1016/j.bbr.2016.08.030.

KAPCSOLAT
Dr. Czéh Boldizsár
Core Facility Vezető
 +36 72 536001 /31231
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